Friday, 20 February 2026

P DMD X BOWEL PERF RISK

 A

Here are concise bullet-point gist taglines you can use (e.g., for a slide or executive summary):

  • Gastrointestinal perforation is a rare but life-threatening complication in Duchenne Muscular Dystrophy (DMD).

  • Evidence limited to case reports and small series; no paediatric-specific guidelines identified.

  • Gastric and colonic perforations reported, often linked to bowel dysmotility and smooth muscle weakness.

  • High peri-operative risk due to cardiorespiratory compromise in DMD.

  • Both operative and non-operative management strategies described in high-risk patients.

  • Early recognition of acute abdominal symptoms is critical to reduce morbidity and mortality.

  • Multidisciplinary management essential (surgical, respiratory, cardiac, nutritional support).

  • Further research needed to guide paediatric risk stratification and management pathways.


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