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Here’s a structured infographic-style breakdown of the differential diagnosis for your case. It’s ready to be formatted into a handover sheet or weekly teaching slide.
🔍 DDx: 15F with PUO, Cervical LN, Bicytopenia, Hilar Changes
| Category | Condition | Clues / Supporting Features |
|---|---|---|
| Malignancy | Hodgkin lymphoma | Cervical LN, B symptoms, mediastinal/hilar nodes |
| ALL / AML | Bicytopenia, constitutional symptoms, bone marrow involvement | |
| Other hematologic cancers | Cytopenias ± organomegaly, constitutional symptoms | |
| Infectious | Tuberculosis (TB) | Indeterminate Quantiferon, cervical LN, hilar changes, prolonged fever |
| EBV / CMV | Fever, fatigue, lymphadenopathy, cytopenias | |
| HIV | Lymphadenopathy, cytopenias, chronic illness, possible opportunistic infections | |
| Bartonella, fungal, brucellosis | Exposure history important, prolonged fever, cytopenias | |
| Autoimmune | Systemic Lupus Erythematosus | Bicytopenia, fever, LN, possible rash, ANA/DS-DNA testing helpful |
| HLH (Hemophagocytic Syndrome) | Persistent fever, cytopenias, ↑ferritin, organomegaly – urgent to consider | |
| Other | Sarcoidosis | Bilateral hilar lymphadenopathy (rare in peds), constitutional symptoms |
| Post-viral or drug-related marrow suppression | Bicytopenia, recent illness or medication exposure |
Would you like me to turn this into a visual slide/infographic format for WhatsApp or teaching purposes?
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