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A recent study by Jeffrey W. Dalley and Mary-Ellen Lynall, published in Science (April 2025), investigates how cancer-induced inflammation affects motivation. (How does cancer affect motivation? - PubMed)
🧠 Key Findings
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Inflammation and Brain Circuits: The study reveals that inflammatory cytokines associated with cancer can disrupt specific brain circuits responsible for motivation, leading to apathy in patients. (How does cancer affect motivation? - Science)
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Neuroimmune Interaction: The research highlights a direct interaction between the immune system and neural pathways, suggesting that inflammation can directly influence brain function related to motivation.
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Implications for Treatment: Understanding this mechanism opens avenues for potential treatments targeting inflammation-induced apathy in cancer patients.
This study provides valuable insights into the biological underpinnings of apathy in cancer patients, emphasizing the role of inflammation in affecting motivation through specific brain circuits. (How does cancer affect motivation? | Request PDF - ResearchGate)
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