Differential diagnosis
Infantile psoriasis is often confused with irritant contact dermatitis, allergic contact dermatitis, seborrheic dermatitis, or candidiasis.
Irritant contact dermatitis is the most common cause of diaper dermatitis, and it results from wet, soiled diapers rubbing against the skin. This only affects the areas of skin exposed to the diaper, and it often affects the prominent skin most in contact with the diaper while sparing the skin folds.6
Allergic contact dermatitis may occur after using a product that contains an ingredient to which the infant is sensitized. This outbreak may involve skin beyond the confines of the diaper area, and it will subside 2-4 weeks after the discontinuation of the culprit product.6
Seborrheic dermatitis presents as erythematous, well-demarcated patches in the diaper area, but it is often erythematous with an overlying greasy scale when present in the scalp, face, ears, and neck. Erythematous plaques may also be present in intertriginous areas in infants, including in the skin folds on legs and arms.6
Candidiasis presents as a bright red eruption that starts in the inguinal folds and may involve the entire diaper area. Erythematous or pustular satellite lesions may be scattered around the periphery of the involved areas.7
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