Midazolam is the most commonly used sedative in Palliative Care (Sykes and Thorns, 2003a)Mean midazolam doses reported range from 22 to 70mg/24h (Mercadante et al., 2009)But individually as high as 240mg/24hIn our study of 238 patients:Overall mean midazolam dose was 25.7 mg/24 hMean midazolam dose for patients receiving sedation throughout the last week of lifewas 54.5 mg/24 h (Sykes and Thorns, 2003b)
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