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This article provides an overview of Bryan Johnson, a 48-year-old tech millionaire who has gained notoriety for his extreme anti-ageing regimen, known as Project Blueprint.
Based on the text provided, here is a breakdown of his philosophy, methods, and the expert skepticism surrounding them.
The Philosophy of "Project Blueprint"
Johnson views himself as a "professional rejuvenation athlete" and an "Olympian for longevity." His goal is to "maximally" reverse the biological age of his organs through a data-driven approach.
Motivation: He began this quest after significant life changes, including leaving the Mormon church and selling his payment company for millions, which now funds his research.
The "Don't Die" Initiative: Beyond physical health, he aims to "upload his thoughts to an AI model" to achieve a form of digital immortality.
Johnson’s Daily Regimen
Johnson spends over six hours a day on his protocols. Key elements mentioned include:
Diet: His last meal is at 11 am. His diet includes ingredients like pomegranate juice extract, pea and hemp protein, and macadamia nut milk.
Monitoring: He uses MRI scans, ultrasounds, blood work, and genetic screening to measure his biological age.
Supplements/Drugs: He has experimented with rapamycin (an immunosuppressant) but stopped due to side effects.
Sleep: He prioritizes sleep as the foundation of his health cascade.
His Top Tip for Longevity
His most accessible recommendation for others is to lower your resting heart rate before bed. To achieve this, he suggests:
Stopping eating 4 hours before sleep.
Engaging in a "wind-down" hour (reading, walking, or meditating).
Avoiding screens and caffeine late in the day.
Avoiding rumination (worrying or obsessing over thoughts), which can spike heart rate by 5 to 25 beats per minute.
Expert Perspectives
While Richard Siow (Director of Ageing Research at King’s College London) finds the self-experimentation interesting, he offers several caveats:
Modifiable vs. Reversible: While biomarkers like inflammation or cholesterol can be improved, Siow argues that definitively claiming one has the "metabolism of a 25-year-old at 40" is difficult because we lack large-scale population datasets for comparison.
Marketing vs. Science: Siow suggests that "biological age" numbers are often more effective for marketing than for clinical accuracy.
Scaling: It is impossible to extrapolate results from a single person (Johnson) to the wider population.
Would you like me to summarize Johnson's specific views on why AI makes his own life expectancy "irrelevant"?
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