Children with Down syndrome are at a significantly higher risk of having severe RSV infections—higher hospital admission, mortality, length of stay, oxygen requirement, ICU admission, need for respiratory support, and additional medication use—than children without Down syndrome,” says Castro-Rodriquez. “Because Down syndrome is the most common chromosomal disorder worldwide and given that RSV is associated with about 28% of all acute lower respiratory tract infection episodes and 13% to 22% of all acute lower respiratory tract infection-related mortality in young children, the results of the current study carry high importance and consequences for public health.”
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