Our endothelium, the inner lining of our blood vessels that controls the function of every artery in our body, “appears to play a critical role in a variety of human disorders, including peripheral vascular disease, stroke, heart disease, diabetes, insulin resistance, chronic kidney failure, [cancer, and blood clots]….” Unfortunately, endothelial cells only live about 30 years, and their replacements don’t seem to function as well. So, “[a]s men and women approach the ages of 40 and 50, there is a progressive decline in endothelial function.” At age 50 or 60, we “can no longer tolerate this risk-factor burden that [we] were once able to tolerate at age 10 or 20,” thanks to this progressive decline in endothelial function.
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