Neutrophil-to-Lymphocyte Ratio on Admission as a Biomarker of Outcomes in Large Vessel–Occlusion Strokes

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“In this retrospective, observational study, researchers examined the relationship between neutrophil to lymphocyte ratio (NLR) with 3-month functional outcomes after stroke due to large artery occlusion after mechanical thrombectomy. Of the 293 subjects who underwent mechanical thrombectomy, patients with lower NLR had increased odds of a good functional outcome (modified Rankin score 0-2) at 3 months. After multivariate analysis, the odds of improved outcome persisted (OR 1.08; 95% CI 1.01-1.16). The investigators also noted a higher risk of symptomatic hemorrhage with each 1-point increase in NLR ratio.”

– Mona Bahouth, MD

Higher NLR at the time of admission is an independent predictor of intracranial hemorrhage and 3-month mortality in patients with large vessel occlusion treated with mechanical thrombectomy.