DWM X DM2 X STROKE RISK X HbA1c
TAKE-HOME MESSAGE
- The authors of this retrospective study examined the relationship between HbA1c and stroke in a cohort of nearly 70,000 patients. In this patient population, hazard ratios demonstrated a U-shape curve wherein both low HbA1c and high HbA1c were associated with an increased risk of stroke. Patients taking antihypertensive, antidiabetic, or lipid-lowering medications had increased risk of stroke at an HbA1c level <6%.
- These results are important and require further investigation as the data suggest that aggressive lowering of HbA1c may increase stroke risk. According to these data, the optimal HbA1c level is between 6% and 7% for stroke prevention in patients with diabetes.
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