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High ventilation breathwork performed while listening to music can induce states described as "psychedelic bliss," marked by powerful feelings of unity, emotional release, and reduced negative emotion, as revealed by a study published September 2, 2025. This altered state is accompanied by distinct changes in brain blood flow: increases are seen in emotion-processing regions like the right amygdala and anterior hippocampus, while self-awareness regions such as the posterior insula experience reduced flow.sciencedaily+4
Study Overview
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Participants practiced 20–30 minutes of fast, cyclic breathing (high ventilation breathwork, HVB) without pauses while listening to evocative music.moneycontrol+1
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The research involved self-reported experiences, neuroimaging (MRI), and physiological measures in experienced practitioners.independent+1
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Reports most commonly described "oceanic boundlessness": sensations of unity, insight, and bliss, mirroring the effects of psychedelic substances.bsms+1
Key Findings
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Emotional Effects: HVB significantly reduced fear and negative emotions across all groups, without causing panic or adverse effects.earth+1
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Brain Changes: MRI scans showed increased blood flow to the right amygdala and anterior hippocampus—regions critical for emotional memory and fear processing—paralleling effects seen with psychedelics.goodnewsnetwork+2
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Decreased Self-Awareness: Blood flow decreased in regions governing bodily and self-awareness (posterior insula and parietal operculum), perhaps facilitating the sense of unity and transcendence.bsms+1
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Physical Activation: Despite physical arousal from breathwork, participants felt emotionally lighter and more open.sciencedaily+2
Therapeutic Implications
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Drug-Free Altered States: HVB with music provides a non-pharmacological, legally accessible route to altered states of consciousness similar to those produced by psychedelics.independent+2
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Potential for Therapy: Researchers suggest HVB could be used as a transformative, natural intervention for stress, PTSD, anxiety, and depression, meriting further investigation.cosmosmagazine+2
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Set and Setting: Experiences were more intense in supportive lab environments, echoing principles from psychedelic therapy research.bsms
Study Caveats
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The research is described as exploratory, with relatively small sample sizes and the need for replication in larger, controlled trials to fully disentangle the roles of breathwork and music.sciencedaily+1
Table: Summary of Neurobiological Changes
| Brain Region Affected | Direction of Blood Flow Change | Associated Experiential State |
|---|---|---|
| Right amygdala | Increased | Emotional memory, fear reductionindependent+1 |
| Anterior hippocampus | Increased | Emotional release |
| Posterior insula, operculum | Decreased | Reduced self-awareness, unity |
This research provides the first neuroimaging-based insight into how breathwork can unlock deep, positive, and sometimes "psychedelic" states in the brain, supporting its growing popularity as a therapeutic tool.earth+3
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