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Here are the key "ageing tipping points" based on the provided image:
Around age 40 (Young Adulthood to Middle Age): The body begins to show initial signs of decline. There's a noticeable increase in age-related molecules, and a decline in muscle mass and skin integrity. The risk of cardiovascular disease rises sharply from 16% to 40%, and the risk of developing Parkinson's and Alzheimer's also increases. The immune system and the ability to metabolize alcohol and caffeine start to decline, and the mortality rate slightly accelerates.
Around age 60 (Entry to Late Middle Age): This period marks a more significant decline. The risk of cardiovascular disease jumps to 75%, and there's a major drop in kidney and immune system function. The brain shows significant signs of ageing, with a corresponding increased risk of Parkinson's and Alzheimer's. Molecular markers of ageing increase and the mortality rate accelerates again.
Around age 80 (Start of Old Age): This is characterized by a significant loss of blood stem cells. There are major shifts in the levels of proteins in blood plasma and increased markers of ageing in the brain. The risk of cardiovascular disease climbs to 85%.
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