Monday, 28 April 2025

RD BK X "Attention is a spotlight — and whatever lies outside its beam can be just as important as what’s illuminated."

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Summary Bullet Points:

Look Again: The Power of Noticing What Was Always There
By Tali Sharot & Cass R. Sunstein


  • Core Concept:

    • People often overlook important aspects of their environment or behavior simply because they are familiar or taken for granted.

    • "Looking again" — consciously re-examining the familiar — can reveal hidden patterns, opportunities, and risks.

  • Why We Miss Things:

    • Adaptation and habituation: We stop noticing things that remain constant.

    • Cognitive biases: Expectations and prior beliefs filter what we perceive and remember.

    • Information overload: Selective attention leads us to ignore seemingly "irrelevant" details.

  • Benefits of Looking Again:

    • Sparks innovation by questioning norms and assumptions.

    • Improves decision-making by identifying overlooked risks or opportunities.

    • Enhances empathy and social understanding by noticing subtle cues in others' behaviors or emotions.

  • Strategies to Foster Re-Examination:

    • Perspective shifts: Intentionally view situations from different angles (e.g., a novice’s view vs. an expert’s view).

    • Prompted reflection: Use questions, feedback, or structured reviews to surface unseen factors.

    • Environmental changes: Small changes in context can refresh awareness and noticing.

  • Applications in Real Life:

    • In business: spotting inefficiencies, unrecognized customer needs, or new markets.

    • In personal life: appreciating relationships, improving habits, recognizing hidden personal strengths.

    • In policymaking: identifying unintended consequences and improving regulations by noticing overlooked factors.

  • Overall Message:

    • To improve outcomes — in work, relationships, and society — we must train ourselves to "look again" at what we think we already know.

    • Curiosity, openness, and deliberate attention are key to uncovering what has always been right in front of us.



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Here are some key quotes from Look Again: The Power of Noticing What Was Always There by Tali Sharot & Cass R. Sunstein:


  • "What we fail to notice can shape our lives just as much as what we do notice."

  • "Familiarity breeds blindness."

  • "When we assume we already know what’s there, we close the door to discovery."

  • "New insights often come not from new information, but from seeing old information differently."

  • "The key to better decisions, innovation, and deeper understanding is learning when — and how — to look again."

  • "Attention is a spotlight — and whatever lies outside its beam can be just as important as what’s illuminated."

  • "It is not ignorance, but unnoticed knowledge, that most often limits us."

  • "Curiosity is not only about seeking the unknown, but about questioning the known."

  • "The power to notice is the power to change."


Would you also like me to pick a few quotes that would work especially well for a presentation slide or social media post? 🎯

N TH IN PRETERMS

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FITNESS


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Summary Bullet Points:

Acta Paediatrica (2025) - Spahic, Zoubovsky, Dietz
EBNEO Commentary on Therapeutic Hypothermia for Preterm Infants (33–35 Weeks GA)


  • Background on HIE and Therapeutic Hypothermia (TH):

    • Hypoxic-ischemic encephalopathy (HIE) causes major morbidity and mortality.

    • TH is proven effective in reducing these risks in term and late preterm infants (>36 weeks GA).

    • Limited evidence exists for TH effectiveness in infants born at 33–35 weeks GA.

  • Key Study – Faix et al. RCT:

    • Multicenter randomized trial evaluating TH vs. normothermia in 33–35 week GA infants with moderate/severe HIE.

    • Result: TH did not reduce death or disability compared to normothermia in this group.

  • Comparison to Previous Studies:

    • The ICE trial (35–42 weeks GA) showed benefits of TH in more mature infants.

    • Small retrospective studies suggested possible TH benefit for preterm infants, influencing AAP guidelines to recommend TH for ≥35 weeks GA.

    • However, some data show higher mortality for 34–35 week infants undergoing TH compared to term infants.

  • Clinical Implications:

    • Infants at 35 weeks GA may resemble 33–34 week infants more than ≥36 week infants in outcomes.

    • Late preterm infants have immature skin barriers and greater surface area-to-weight ratio → higher vulnerability to cold stress and related risks with TH.

  • Practice Considerations:

    • Growing use of TH in preterm HIE despite limited evidence.

    • Suggests involving informed consent and shared decision-making with caregivers when considering TH for <36 week GA infants.

    • Until guidelines are updated, clinicians may face medical-legal challenges if deviating from AAP recommendations.

  • Future Directions:

    • Urgent need for further research with larger cohorts and stratification by gestational age.

    • Calls for cross-institutional collaboration to better define TH’s role in infants <37 weeks GA.

    • Aim to refine national and institutional guidelines based on emerging evidence.


References:

  1. Current TH use and effectiveness.

  2. AAP recommendations based on earlier studies.

  3. Faix et al. (2025) RCT outcomes.

  4. Risks and cold stress in late preterm infants.

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N LONG DCC

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Summary Bullet Points:

Acta Paediatrica (2025) - Katheria
EBNEO Commentary on Physiological Versus Time-Based Cord Clamping in Very Preterm Infants


  • Historical Context:

    • Intact cord resuscitation dates back to the 14th century, where clamping was delayed until lung aeration occurred.

    • Early observational studies highlighted the benefits of maintaining placental circulation during initial breathing.

  • Key Study – ABC3 Trial:

    • Largest RCT comparing intact cord resuscitation vs. shorter, time-based delayed cord clamping (DCC).

    • Patient-Centered Approach: Cord clamped when infants reached:

      • Peripheral oxygen saturation ≥85%

      • <40% supplemental oxygen

      • Heart rate >100 bpm

    • Minimum cord clamping time: 3 minutes; maximum: 10 minutes.

    • Early clamping if excessive maternal blood loss occurred.

    • Mean clamping time in intervention group: ~6 minutes.

  • ILCOR Recommendations (2024):

    • Consider deferring cord clamping for ≥120 seconds (long DCC) when:

      • No contraindications present.

      • Adequate resources (skilled team, training, equipment, space, thermal management).

    • Insufficient evidence to recommend long DCC universally—more research needed.

    • Emphasis on feasibility, cost-effectiveness, and equity considerations.

  • Key Findings & Considerations:

    • Infants with long DCC + intact cord resuscitation had lower initial temperatures.

    • Improved outcomes correlated with team experience and coordination.

    • Highlights the importance of practice, training, and behavioral skill development in neonatal resuscitation.

  • Outcomes:

    • No significant differences in primary outcomes.

    • Secondary benefits observed:

      • Fewer red blood cell transfusions.

      • Lower rates of late-onset sepsis.

      • Reduced parental anxiety (family-centered outcomes).

    • Ongoing follow-up for long-term neurodevelopmental outcomes.

  • Future Implications:

    • Potential neurodevelopmental benefits in preterm infants due to improved hemoglobin levels and reduced transfusions.

    • Previous research (Andersson et al.) showed improved 4-year outcomes in term infants with 3-minute DCC vs. early clamping.

    • Preterm infants may experience greater long-term benefits due to higher neurodevelopmental risk.


References:

  1. Historical context of intact cord resuscitation.

  2. ILCOR (2024) consensus and recommendations.

  3. Andersson et al. on long-term outcomes of DCC in term infants.

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All in all, suffering souls need to develop a new way of thinking and

feeling. And for that, they need guidance that helps them gain

perspective as well as the ability to view things as they are. This, in

turn, will help these souls practice detachment from their own

suffering and all external influences that trigger and fuel their

suffering!

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STARK CHOICE X UNCERTAIN FUTURE

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A   WITNESS MTP AND  RESEARCH LON 

“The Self is ear of the ear, mind of the mind, speech of speech. He is also breath of the breath, and eye of the eye. Having given up the false identification of the Self with the senses and the mind, and knowing the Self to be Brahman, the wise, on departing this life, become immortal.” The ear, mind, speech, breath, and eye are only instruments, only messengers. The one who causes them to function, the hearer of hearing, the witness of the mind and thought, the understander of speech, the source of the breath and the seer of seeing, is the Atman, the Self. External experience may be illusory, but if we trace the illusion back and back to the perceiver of perception we will find the reality that is the Self. In a motion picture we see so many images, so many illusions, but when the picture stops we see the pure white screen that was behind it all the time, without which no picture would have been possible. Such is the Self. Knowing the Self to be none other than Brahman, the Absolute, rebirth is no more. Swami Prabhavananda has translated the word dhira as “the wise,” but in actuality dhira means those who are steadfast–in this instance those who are firmly established in the practice of yoga and in the realization arising from yoga.

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Dareer limiting complaint

Reading between the lies

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No straight road takes you there