Saturday, 19 July 2025

M ACROMETASTSES

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Acrometastases are metastatic cancer lesions that occur in the extremities of the body — specifically the hands or feet, distal to the elbows or knees.


🔬 Definition:

  • Acro- = extremity (Greek)

  • Metastasis = spread of cancer from a primary site to a distant location

🧠 Acrometastases = metastatic cancer in the bones of the hands or feet


🧠 Key Facts:

Aspect Details
Rarity Extremely rare — accounts for 0.1% of all bone metastases.
Common Primary Tumors Most often from lung cancer (especially squamous cell), but also breast, kidney, and colon cancers.
Most Common Site Distal phalanges of the hand, particularly the third finger. Foot involvement is less frequent.
Symptoms Pain, swelling, redness, limited motion — can resemble infection (osteomyelitis) or arthritis.
Diagnosis X-rays, MRI, bone scans, and biopsy to distinguish from infection or primary bone tumors.
Treatment Often palliative: radiation, surgery (if painful), or amputation. Systemic therapy depends on primary tumor.

🧩 Why Is It Important?

  1. May be the first sign of an undiagnosed internal cancer.

  2. Mimics benign conditions — often misdiagnosed.

  3. Indicates advanced-stage disease with poor prognosis.


🩺 Clinical Pearl:

If an adult presents with unexplained pain or swelling in a finger or toe — especially with a history of cancer — think acrometastasis, even though it’s rare.


Would you like visual examples (e.g., radiographic images), or a short summary suitable for a medical note or patient explanation?

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