P URO STONES

In summary, this study provides preliminary evidence of female vs. male specific differences in pediatric urinary stone presentation, management, laboratory results, and outcomes. Based on our results, follow-up studies to validate differential height z-scores, increased urine LE in female urinary stone patients, and increased rates of volume depletion markers in male urinary stone patients are needed. We identified that an increasing BUN/creatinine ratio is associated with increasing eGFR and 9% of patients have labs consistent with glomerular hyperfiltration. A high protein diet and/or chronic hypohydration may be a mechanism, with an origin in the pediatric age range, for the association between CKD and urinary stone disease. Additionally, pediatric urinary stone management would benefit from guidelines regarding the indications for CT to limit radiation exposure, when DXA scans are indicated, and consensus on when to initiate pharmacological therapy