Monday, 20 November 2017

ENTEROCOCCUS X LINEZOLID RESISTANCE

Increasing linezolid resistant Enterococcus in a Children’s Hospital

Bagga, Bindiya MD; Buckingham, Steve MD; Arnold, Sandra MD; Nesbitt, Amanda MLS(ASCP)CM; Guimera, Don RN; Lee, Kelley PharmD
The Pediatric Infectious Disease Journal:
We report a reduction in susceptibility to linezolid among Enterococcus isolates (98% in 2007 vs. 46% in 2014) in parallel with a 5- fold increase in linezolid use. A direct association could not be established as the majority of patients with linezolid non-susceptible isolates did not have prior linezolid exposure. Nosocomial transmission of the non-susceptible isolates could certainly have contributed.

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